The syntheses of nonnucleoside, HIV-1 reverse transcriptase inhibitors containing a CF 2 group: The SRN1 reactions of 2-(bromodifluoromethyl) benzoxazole with the …
CR Burkholder, WR Dolbier, M Médebielle
文献索引：Burkholder, Conrad R.; Dolbier Jr., William R.; Medebielle, Maurice Journal of Fluorine Chemistry, 2000 , vol. 102, # 1-2 p. 369 - 376
In an effort to prepare new fluorine-containing compounds which are active against HIV, the SRN1 reactions of 2-(bromodifluoromethyl) benzoxazole (5) with the anions of heterocyclic thiols and phenolic compounds were carried out. The products (6a–j and 7a–f), which all ...
