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Semisynthetic penicillins. III. Heterocyclic penicillins

AW Chow, NM Hall, JRE Hoover…

文献索引:Chow,A.W. et al. Journal of Medicinal Chemistry, 1966 , vol. 9, p. 551 - 555

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被引用次数: 7

摘要

In part I of this series2 the preparation of a group of 2-biphenylylpenicillins which are highly active against a resist'ant3 strain of staphylococcus was reported. In a subsequent paper4 a variety of further structural modifications of the 2-biphenylyl side chain was reported. These studies indicated that replacing eit'her benzene ring with a-and 0-naphthyl resulted in compounds having activity similar to that of the parent conipound, while replacing either ...