Novel photoaffinity label for the dopamine D2 receptor: synthesis of 4-amino-5-iodo-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl] benzamide (iodoazidoclebopride, …
Conclusion. In the Japanese population, as well as the European and American populations, FH occurs at a frequency of 1 in 500. It is closely associated with premature atherosclerotic heart disease. The increased levels of LDL in FH is believed to accelerate atherosclerosis. FH is a disorder characterized by the defect in LDL receptor, which causes a decrease in LDL uptake by the cell. The decreased LDL uptake, in turn, results in higher ...
