Quinolines. V. Some Polysubstituted 4-(4'-Diethylamino-1'-methylbutylamino)-quinolines1

EA Steck, LL Hallock, AJ Holland…

文献索引：Steck et al. Journal of the American Chemical Society, 1948 , vol. 70, p. 1012,1014

全文：HTML全文

被引用次数: 13

摘要

Chloroquine (SN 7618, 7-chloro-4-(4 '-diethylamino-1-methylbutylamino)-quinoline) 2, 8 has been found to be the most effective of the quinoline antimalarials bearing the basic chain in position 4. In our program, which has involved the preparation of numerous analogous compounds bearing an alkyl group in the pyridine m~ iety,~ we have attempted to evaluate the influence of the position and nature of several groups upon antiplasmodial activity. ...