Cerium chloride (III) promoted nucleophilic addition of organolithium reagents to α-diphenylphosphinoyl ketones. An efficient method for the synthesis of horner-wittig …
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Reaction of α-diphenylphosphinoyl ketones with organolithium reagents, in the presence of anhydrous CeCl 3 in THF at −78°C, affords β-hydroxyalkylphosphine oxides in fair to good yields. These are essential to obtain olefins with β-carbon disubstituted.
