Tetrahedron letters

Cerium chloride (III) promoted nucleophilic addition of organolithium reagents to α-diphenylphosphinoyl ketones. An efficient method for the synthesis of horner-wittig …

G Bartoli, L Sambri, E Marcantoni, M Petrini

Index: Bartoli; Sambri; Marcantoni; Petrini Tetrahedron Letters, 1994 , vol. 35, # 45 p. 8453 - 8456

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Citation Number: 11

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Reaction of α-diphenylphosphinoyl ketones with organolithium reagents, in the presence of anhydrous CeCl 3 in THF at −78°C, affords β-hydroxyalkylphosphine oxides in fair to good yields. These are essential to obtain olefins with β-carbon disubstituted.