Il Farmaco

Disoxaril-related 3-(diethylamino)-5-phenylisoxazoles

M Mazzei, R Dondero, B Ledda, F Demontis, L Vargiu

文献索引：Mazzei, Mauro; Dondero, Ramona; Ledda, Bernardetta; Demontis, Francesca; Vargiu, Laura Farmaco, 2000 , vol. 55, # 2 p. 119 - 124

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被引用次数: 4

摘要

Previous research has shown that 3-(dialkylamino)-5-phenylisoxazoles possessing a compact structure were active against HRV-2 and, consequently, presented a type B activity. In this paper, 3-(diethylamino)-5-phenylisoxazoles, which are structurally more elongated and related to Disoxaril, were synthesized in view to attempt type A activity against HRV-14. Unfortunately, all tested compounds were devoid of activity against HRV-14 (and HIV-1) or ...