Ir??and Ru??Catalyzed Sequential Reactions: Asymmetric α??Alkylative Reduction of Ketones with Alcohols

G Onodera, Y Nishibayashi…

文献索引：Onodera, Gen; Nishibayashi, Yoshiaki; Uemura, Sakae Angewandte Chemie - International Edition, 2006 , vol. 45, # 23 p. 3819 - 3822

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被引用次数: 112

摘要

Transition-metal-catalyzed asymmetric reduction of prochiral ketones is one of the most intensive subjects in organic synthesis.[1, 2] Among a variety of systems for the catalytic reduction, ruthenium-catalyzed hydrogenation, and transfer hydrogenation of prochiral ketones have been developed and used as reliable synthetic methods to obtain reduced alcohols with a highto-excellent enantioselectivity.[1, 2] We have also reported the ...