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Synthesis of N-aryl derivatives of succinimide and phthalimide

SI Zav'yalov, AG Zavozin, LB Kulikova…

文献索引:Zav'yalov; Zavozin; Kulikova; Ezhova; Kravchenko Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 1 p. 43 - 44

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被引用次数: 3

摘要

The N-aryl derivatives of succinimide and phthalimide exhibit fungicide action [1] and hypolipidemic activity [2]. These derivatives are obtained by heating aromatic amines with succinic (I) and phthalic (II) anhydrides in cymene [2] or in a mixture of AcOH, AcONa, and Ae20 [3]. Methods also have been reported for synthesizing these derivatives by in- teraction of arylamines with dichloroanhydride of succinic acid [4], N-hydroxyphthalimide [5], and thiophthalic anhy- dride [6], or by ...