Chemical Communications

Enantioselective bromolactonization of cis-1, 2-disubstituted olefinic acids using an amino-thiocarbamate catalyst

CK Tan, C Le, YY Yeung

文献索引：Tan, Chong Kiat; Le, Chencheng; Yeung, Ying-Yeung Chemical Communications, 2012 , vol. 48, # 46 p. 5793 - 5795

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被引用次数: 60

摘要

A facile, highly regio-and enantioselective amino-thiocarbamate-catalyzed bromolactonization of cis-1, 2-disubstituted olefinic acids has been developed. The use of the enantio-enriched lactones in the synthesis of chiral synthetic intermediates is also demonstrated.