A metal-free diverse synthesis of difluoromethylthioethers and difluorobis (arylthio) methanes from RSX (X= SR, Cl, SO2Ph) and TMSCF2H

JB Han, HL Qin, SH Ye, L Zhu…

文献索引：Mehta, Vaibhav P.; Greaney, Michael F. Organic Letters, 2013 , vol. 15, # 19 p. 5036 - 5039

全文：HTML全文

被引用次数: 6

摘要

... permeability, metabolic stability, and bioavailability.(1, 2) The introduction of fluorine atoms into biologically active organic frameworks has ... reagents like HCF 2 Cl, FSO 2 CF 2 CO 2 M, BrCF 2 P(O)(OEt ... 3 SiF 2 ] as base, which is more soluble in DMF than [Me 4 N]F, provided 2a ...