Organic letters

Stereoselective Aldol Reaction of Glutarimides Using Pseudo C 2 Symmetry

Y Watanabe, T Yamazaki, T Kubota

文献索引：Watanabe, Yohsuke; Yamazaki, Takashi; Kubota, Toshio Organic Letters, 2010 , vol. 12, # 2 p. 268 - 271

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被引用次数: 2

摘要

In recent years, trifluoromethyl-containing compounds have been growing in importance and value because of their strategic applications in the medicinal and functional materials fields.(1) We have pursued the development of the syntheses of chiral CF 3 -containing compounds by use of desymmetrization of β-CF 3 -substituted glutaric acid derivatives; their pseudo C 2 symmetry enables concomitant stereocontrol of two or three chiral centers by a single nucleophilic ...