When tetramethylene chlorohydrin was substituted for 4-chlorobutyl acetate in the above sequence, the sultone was formed in only 587, yield. This lower yield is probably due to a competing reaction in the first step of the synthesis whereby tetramethylene chlorohydrin loses hydrogen chloride and forms tetrahydrofuran. In the reaction of the chlorohydrin with sodium sulfite the odor of sulfur dioxide was observed; this could arise from the action of ...
