The Journal of Organic Chemistry

Directing effects in homogeneous hydrogenation with [Ir (cod)(PCy3)(py)] PF6

RH Crabtree, MW Davis

文献索引：Crabtree, Robert H.; Davis, Mark W. Journal of Organic Chemistry, 1986 , vol. 51, # 14 p. 2655 - 2661

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被引用次数: 248

摘要

The presence of a ligating group, eg, OH, C02Me, C= O, or OMe, on an olefinic substrate is shown to direct the attack of the hydrogenation catalyst [Ir (cod)(PCy~)(C~ H~ N)] PFs/H2/CHzClz from the face of the molecule containing the directing group. Isomerization is a minor side reaction in the cases studied. The origin of this effect is discussed and a model intermediate isolated.