The Journal of Organic Chemistry

Asymmetric Allylation and Reduction on an Ephedrine-Derived Template: Stereoselective Synthesis of α-Hydroxy Acids and Derivatives

SV Pansare, RG Ravi, RP Jain

文献索引：Pansare, Sunil V.; Ravi, R.Gnana; Jain, Rajendra P. Journal of Organic Chemistry, 1998 , vol. 63, # 12 p. 4120 - 4124

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被引用次数: 40

摘要

The asymmetric synthesis of R-hydroxy acids continues to be an area of active interest due to their utility as chiral building blocks. 1 Among the several synthetic approaches to R- hydroxy acids, the stereoselective addition of carbon nucleophiles to chiral R-keto acid derivatives has been extensively investigated. 2 We describe here a stereoselective synthesis of R-alkyl R-allyl R-hydroxy amides, R-alkyl R-hydroxy acids, and RH R-hydroxy ...