Dicationic pyridium porphyrins appending different peripheral substituents: Synthesis and studies for their interactions with DNA

…, L Ren, B Chen, F Liang, X Zhou, T Jia, X Cao

文献索引：Wu, Song; Li, Zheng; Ren, Lige; Chen, Bo; Liang, Feng; Zhou, Xiang; Jia, Tao; Cao, Xiaoping Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 9 p. 2956 - 2965

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被引用次数: 39

摘要

Twelve trans-dicationic pyridium porphyrins appending different peripheral substituents were synthesized and their abilities to bind and cleave DNA under irradiation have been investigated. Their binding modes to DNA were studied by UV–vis spectroscopy, circular dichroism. The apparent constants were measured by EB competitive fluorescence method and most of them were in the range of 104–105M− 1. We found that both the position of ...