An efficient process of racemization of 3-(carbamoylmethyl)-5-methylhexanoic acid: a pregabalin intermediate

AB Chavan, GC Maikap, MK Gurjar

文献索引：Organic Process Research and Development, , vol. 13, # 4 p. 812 - 814

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被引用次数: 7

摘要

... Organic Process Research & Development. ... The resulting symmetrical 3-isobutylglutaric acid (2) was transformed into racemic 4 by the documented procedure.(2, 3). figure ... acid in a one-pot reaction sequence (Scheme 5). This protocol has made the process of manufacturing ...