An efficient process of racemization of 3-(carbamoylmethyl)-5-methylhexanoic acid: a pregabalin intermediate

AB Chavan, GC Maikap, MK Gurjar

Index: Organic Process Research and Development, , vol. 13, # 4 p. 812 - 814

Full Text: HTML

Citation Number: 7

Abstract

... Organic Process Research & Development. ... The resulting symmetrical 3-isobutylglutaric acid (2) was transformed into racemic 4 by the documented procedure.(2, 3). figure ... acid in a one-pot reaction sequence (Scheme 5). This protocol has made the process of manufacturing ...