J. Med. Chem

Joaquin Campos Rosa, Dimitrios Galanakis, C. Robin Ganellin,*, Philip M. Dunn,| and

DH Jenkinson

文献索引：Rosa, Joaquin Campos; Galanakis, Dimitrios; Ganellin, C. Robin; Dunn, Philip M.; Jenkinson, Donald H. Journal of Medicinal Chemistry, 1998 , vol. 41, # 1 p. 2 - 5

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被引用次数: 77

摘要

Small conductance Ca2+-activated K+(SKCa) channels comprise a widely distributed but relatively little studied class of K+ channels. 1 Selective blockade of SKCa channels may find application in the therapy of myotonic muscular dystrophy, 2 gastrointestinal dysmotilities (Dunn, PM; Jenkinson, DH, unpublished results), disorders of memory, 3 narcolepsy, 4 and alcohol abuse. 5 Furthermore, SKCa channel blockers will be ...