Design, synthesis and antifungal evaluation of 1-(2-(2, 4-difluorophenyl)-2-hydroxy-3-(1H-1, 2, 4-triazol-1-yl) propyl)-1H-1, 2, 4-triazol-5 (4H)-one

Y Jiang, Y Cao, J Zhang, Y Zou, X Chai, H Hu…

文献索引：European Journal of Medicinal Chemistry, , vol. 46, # 7 p. 3135 - 3141

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被引用次数: 17

摘要

... European Journal of Medicinal Chemistry. ... Yield 84%, mp: 74.1–75.0 °C; 1 HNMR δ (ppm): 8.17 (1H, s, triazole–H), 7.85 (1H, s, triazole–H), 6.80–7.63 (9H, m, Ar–H), 5.84 (1H, s, –OH), 4.72 (2H, m, triazole–CH 2 –), 4.18–4.65 (2H, dd, J = 14.7 Hz, –CH 2 –triazolone); IR (KBr ...