Efficient Construction of C N Double Bonds via Acceptorless Dehydrogenative Coupling

X Sun, Y Hu, S Nie, Y Yan, X Zhang…

文献索引：Sun, Xiang; Hu, Yu; Nie, Shao-Zhen; Yan, Yun-Yun; Zhang, Xue-Jing; Yan, Ming Advanced Synthesis and Catalysis, 2013 , vol. 355, # 11-12 p. 2179 - 2184

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被引用次数: 7

摘要

Abstract: The efficient construction of C= N double bonds has been achieved by the Ir- catalyzed intramolecular acceptorless dehydrogenative cross-coupling of tertiary amines and amides. An iridium/2-hydroxypyridine complex was identified as the highly efficient catalyst. A number of quinazolinone derivatives was prepared in excellent yields. An iridium- mediated CÀH activation mechanism is proposed. This finding provides an ...