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Tetrahedron Letters

Phosphoric acid mediated tautomerism of imines: addition of a secondary enamine intermediate to aldehydes

LO Davis, MA Putri, CL Meyer, CP Durant

文献索引:Davis, Lindsey O.; Putri, Marcella A.; Meyer, Caitlin L.; Durant, Christopher P. Tetrahedron Letters, 2014 , vol. 55, # 19 p. 3100 - 3103

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摘要

Abstract A phosphoric acid derivative has been shown to promote the addition between an imine and several aldehyde substrates through an enamine intermediate to give cross-aldol condensation products. The reaction scope and preliminary mechanistic investigations will be presented.