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Bioorganic & medicinal chemistry

Synthesis and evaluation of α, α-disubstituted-3-mercaptopropanoic acids as inhibitors for carboxypeptidase A and implications with respect to enzyme inhibitor …

HS Lee, DH Kim

文献索引:Bioorganic and Medicinal Chemistry, , vol. 11, # 22 p. 4685 - 4691

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被引用次数: 12

摘要

... Bioorganic & Medicinal Chemistry. ... 2 Of numerous zinc proteases, carboxypeptidase A (CPA) 6 is most extensively studied and has served as a model target enzyme for the development of inhibitor design strategies 7 that can be applied to zinc proteases of medicinal interest. ...