Journal of Chemistry

Syntheses, characterization and antimicrobial evaluation of some 1, 3, 5-trisubustituted pyrazole derivatives

V Gautam, V Chawla, SK Saraf

文献索引：Gautam, Vertika; Chawla, Viney; Sonar, Pankaj K.; Saraf, Shailendra K. E-Journal of Chemistry, 2010 , vol. 7, # 4 p. 1190 - 1195

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被引用次数: 13

摘要

A series of 1, 3, 5-trisubustituted pyrazole derivatives were synthesized and screened for antimicrobial activity. The compounds (2j-o) were evaluated against two gram-positive and two gram-negative bacteria and one fungus, at concentrations of 10 µg/mL and 50 µg/mL. The compounds were founds to be inactive against P. aeruginosa and A. niger but exhibited moderate activity against B. subtilis, E. coli and S. aureus. It can be concluded that the ...