Structure-based bioisosterism design, synthesis and biological evaluation of novel 1, 2, 4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs

P Zhan, X Li, Z Li, X Chen, Y Tian, W Chen, X Liu…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 23 p. 7155 - 7162

全文：HTML全文

被引用次数: 16

摘要

... Bioorganic & Medicinal Chemistry Letters. ... b Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium. Received 13 ... the central core in bioactive lead molecules, a common and efficient 'follow-on'-based medicinal chemistry strategy to ...