Bioorganic & medicinal chemistry

An efficient synthesis and biological activity of substituted p-benzoquinones

M Batra, P Kriplani, C Batra, KG Ojha

文献索引：Batra, Manoj; Kriplani, Prashant; Batra, Chhavi; Ojha Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 24 p. 8519 - 8526

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被引用次数: 15

摘要

An efficient synthesis of 2, 5-diarylamino-3, 6-dichloro-1, 4-benzoquinone derivatives has been achieved by condensing mono substituted anilines with tetrachloro-p-benzoquinone in presence of fused sodium acetate as condensing agent under microwave irradiation without any solvent. All the synthesized compounds were tested for their antibacterial and antitumour activity using standard drugs.