Bioorganic & medicinal chemistry

An efficient synthesis and biological activity of substituted p-benzoquinones

M Batra, P Kriplani, C Batra, KG Ojha

Index: Batra, Manoj; Kriplani, Prashant; Batra, Chhavi; Ojha Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 24 p. 8519 - 8526

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Citation Number: 15

Abstract

An efficient synthesis of 2, 5-diarylamino-3, 6-dichloro-1, 4-benzoquinone derivatives has been achieved by condensing mono substituted anilines with tetrachloro-p-benzoquinone in presence of fused sodium acetate as condensing agent under microwave irradiation without any solvent. All the synthesized compounds were tested for their antibacterial and antitumour activity using standard drugs.