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Synthesis of mono-substituted derivatives of 6-aminoquinoline

…, XX Yuan, JH Yu, C Jia, YS Wang, HJ Zhang…

文献索引:Lan, Tian; Yuan, Xian Xia; Yu, Jiang Hong; Jia, Chao; Wang, Yu Shi; Zhang, Hui Juan; Ma, Zi Feng; Ye, Wei Dong Chinese Chemical Letters, 2011 , vol. 22, # 3 p. 253 - 255

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被引用次数: 4

摘要

Several 6-aminoquinoline derivatives, which could be used in drug design, have been synthesized. The reaction conditions were comparatively studied, and the p-chloroaniline was used as optimum oxidant in Skraup–Doebner–Von Miller reaction. The nitro group was reduced effectively by SnCl2 with no halo-removed occurred.