Synthesis and biological activities of novel aryl indole-2-carboxylic acid analogs as PPARγ partial agonists

JF Dropinski, T Akiyama, M Einstein…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 22 p. 5035 - 5038

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被引用次数: 52

摘要

... Bioorganic & Medicinal Chemistry Letters. ... A medicinal chemistry effort was initiated based on the interesting biological profile of compound 1a ... The latter was converted to compounds 33–39 using either the previously discussed copper coupling or halide displacement chemistry. ...