Tetrahedron letters

Simple and facile reduction of azides to amines: synthesis of DNA interactive pyrrolo [2, 1-c][1, 4] benzodiazepines

A Kamal, P Reddy, DR Reddy

文献索引：Kamal, Ahmed; Reddy; Reddy, D.Rajasekhar Tetrahedron Letters, 2002 , vol. 43, # 37 p. 6629 - 6631

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被引用次数: 40

摘要

The reduction of aromatic azido compounds to the corresponding amines with hydriodic acid has been investigated and found to result in high yields. This reductive methodology which proceeds under non refluxing condition has been extended for the synthesis of DNA- interactive pyrrolo [2, 1-c][1, 4] benzodiazepine antibiotics.