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Diaryl ester prodrugs of FR900098 with improved in vivo antimalarial activity

A Reichenberg, J Wiesner, C Weidemeyer…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 6 p. 833 - 835

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被引用次数: 109

摘要

... Bioorganic & Medicinal Chemistry Letters. Volume 11, Issue 6, 26 March 2001, Pages 833–835. ... Prodrugs of FR900098 with increased activity after oral administration were obtained by chemical modification of the phosphonate moiety to yield phosphodiaryl esters. ...