Diaryl ester prodrugs of FR900098 with improved in vivo antimalarial activity

A Reichenberg, J Wiesner, C Weidemeyer…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 6 p. 833 - 835

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Citation Number: 109

Abstract

... Bioorganic & Medicinal Chemistry Letters. Volume 11, Issue 6, 26 March 2001, Pages 833–835. ... Prodrugs of FR900098 with increased activity after oral administration were obtained by chemical modification of the phosphonate moiety to yield phosphodiaryl esters. ...