Synthesis and pharmacological activity of 2-aryl-3-ethoxy-carbonyl-5-hydroxybenzofurans

…, TM Gololobova, AA Stolyarchuk, GI Stepanyuk…

文献索引：Zotova, S. A.; Gololobova, T. M.; Stolyarchuk, A. A.; Stepanyuk, G. I.; Bobruk, V. P.; et al. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 1 p. 26 - 30 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 1 p. 35 - 39

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被引用次数: 1

摘要

An intensive search for pharmaceuticals of the benzofuran series led to the development of the cardiovascular drug fenicarberan (2-phenyl-3-ethoxycarbonyl-4-dimethylaminomethyl-5- hydroxybenzofuran hydrochloride)[3]. There have also been reports in the literature that a considerable number of 2-aryl-5-hydroxybenzofurans display antifungal [13], antibacterial [ii],~-adrenoblocking [I0], anticonvulsant and psychotropic activity [2, 7]. For this reason, it ...