Synthesis and evaluation of pN, N-dialkyl substituted chalcones as anti-cancer agents

…, JS Kumar, C Bicknese, JL Johnson, M Williams

文献索引：Nelson, Grady; Alam, Mohammad A.; Atkinson, Tyler; Gurrapu, Shirisha; Sravan Kumar; Bicknese, Chris; Johnson, Joseph L.; Williams, Michael Medicinal Chemistry Research, 2013 , vol. 22, # 10 p. 4610 - 4614

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被引用次数: 8

摘要

Abstract Several new N, N-dialkyl substituted chalcones (chalconoids or benzylideneacetophenones) have been synthesized via the condensation of corresponding N, N-dialkylbenzaldehyde with various aryl methyl ketones. All the chalcones have been synthesized from readily available and cheap starting materials under environmentally benign conditions in very high yields without work up and column chromatographic ...