Ryanoids and related compounds Chemoselective electrocatalytic hydrogenation of alkyl α-pyrrole carboxylates: Selective hydrogenation of ryanodine

…, H Ménard, V Moreau, F Laplante

文献索引：Ruest, Luc; Menard, Hugues; Moreau, Vincent; Laplante, Francois Canadian Journal of Chemistry, 2002 , vol. 80, # 12 p. 1662 - 1667

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被引用次数: 14

摘要

A study of the electrocatalytic hydrogenation (ECH) process of pyrrole and different alkyl pyrrole-2-carboxylates is presented. Once hydrogenated, the alkyl pyrrole-2-carboxylate becomes an ester of proline, an important natural amino acid. The process is chemoselective to the pyrrole ring. Ryanodine is a natural ryanoid known to be biologically active. The tetrahydroryanodine derivative thus obtained may now represent a molecule of ...