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Synthetic Communications®

Facile Synthesis of Second-Generation Dendrons with an Orthogonal Functional Group at the Focal Point

RK Cheedarala, V Sunkara, JW Park

文献索引:Cheedarala, Ravi Kumar; Sunkara, Vijaya; Park, Joon Won Synthetic Communications, 2009 , vol. 39, # 11 p. 1966 - 1980

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被引用次数: 3

摘要

Abstract Facile synthesis of second-generation dendrons with an aldehyde, epoxy, or t-Boc group at the focal point and nine carboxylic acid groups at the periphery is reported. The scheme includes a coupling of the first-generation dendrons and a two-step, one-pot reaction that proceeds through a Boc deprotection and in situ conjugation at the focal point.