Synthesis and evaluation of novel sulfenamides as novel anti Methicillin-resistant Staphylococcus aureus agents

…, ZS Li, B Ren, ZM Li, H Dai, LX Zhang, JG Wang

文献索引：Shang, Jian-Li; Guo, Hui; Li, Zai-Shun; Ren, Biao; Li, Zheng-Ming; Dai, Huan-Qin; Zhang, Li-Xin; Wang, Jian-Guo Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 3 p. 724 - 727

全文：HTML全文

被引用次数: 8

摘要

A total of 29 novel sulfenamide compounds were synthesized, spectroscopically characterized and evaluated in vitro for antimicrobial activity against various infectious pathogens. Compounds 1b and 2c exhibited potent inhibition against clinical Methicillin- resistant Staphylococcus aureus (MRSA) strains with minimum inhibitory concentration (MIC) values of 1.56 μg/mL.

~73%

~46%

A new class of anti-HIV-1 agents targeted toward the nucleoc...

[Domagala, John M.; Bader, John P.; Gogliotti, Rocco D.; Sanchez, Joseph P.; Stier, Michael A.; Song, Yuntao; Vara Prasad; Tummino, Peter J.; Scholten, Jeffrey; Harvey, Patricia; Holler, Tod; Gracheck, Steve; Hupe, Donald; Rice, William G.; Schultz, Robert Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 3 p. 569 - 579]

A general and highly regio and stereoselective method for th...

[Nandi, Bidisha; Kundu, Nitya G. Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 14 p. 1649 - 1655]

Chemistry of sulfenic acids. 7. Reason for the high reactivi...

[Davis, Franklin A.; Jenkins, Linda A.; Billmers, Robert L. Journal of Organic Chemistry, 1986 , vol. 51, # 7 p. 1033 - 1040]

Concise Approach to Benzisothiazol-3 (2 H)-one via Copper-Ca...

[Shimizu, Masao; Kikumoto, Hisashi; Konakahara, Takeo; Gama, Yasuo; Shibuya, Isao Heterocycles, 1999 , vol. 51, # 12 p. 3005 - 3012]

Electrosynthesis of fluorinated benzo [b] thiophene derivati...

[Yin, Bin; Inagi, Shinsuke; Fuchigami, Toshio Synlett, 2011 , # 9 p. 1313 - 1317]