Tetrahedron letters

An improved total synthesis of spermatinamine, an inhibitor of isoprenylcysteine carboxy methyltransferase

N Ullah, SA Haladu, BA Mosa

文献索引：Ullah, Nisar; Haladu, Shamsuddeen A.; Mosa, Basem A. Tetrahedron Letters, 2011 , vol. 52, # 2 p. 212 - 214

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被引用次数: 6

摘要

An improved total synthesis of spermatinamine, an inhibitor of the anticancer target, isoprenylcysteine carboxy methyltransferase (Icmt) was accomplished from the commercially available 3, 4-dibromo-4-hydroxybenzaldehyde via a high yielding reaction sequence in an overall yield of 31%.