L-proline-catalyzed direct intermolecular asymmetric aldol reactions of 1-phenylthiocycloalkyl carboxaldehydes with ketones. Easy access to spiro-and fused- …
…, A Frongia, R Guillot, PP Piras, F Secci, M Spiga
文献索引：Bernard, Angela M.; Frongia, Angelo; Guillot, Regis; Piras, Pier P.; Secci, Francesco; Spiga, Marco Organic Letters, 2007 , vol. 9, # 3 p. 541 - 544
Acid-catalyzed ring expansion of chiral cyclopropyl and cyclobutyl derivatives for the synthesis of carbo-and heterocyclic compounds is reported. The starting materials have been successfully prepared by l-proline-catalyzed direct asymmetric aldol reactions of 1- phenylthiocycloalkyl carboxaldehydes with ketones.
