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Tetrahedron

Epoxidation of Peptidyl Olefin Isosteres. Stereochemical Induction Effect of Chiral Centers at Four Adjacent C α Positions

N Perlman, M Livneh, A Albeck

文献索引:Perlman, Nurit; Livneh, Mordechai; Albeck, Amnon Tetrahedron, 2000 , vol. 56, # 11 p. 1505 - 1516

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被引用次数: 9

摘要

Four tripeptidyl olefin isosteres were prepared, each of which contains a single chiral center derived from the bulky amino acid phenylalanine at positions corresponding to the P2–P′ 2 positions of a protease substrate. The effect of these chiral centers on the stereochemical ...