前往化源商城

Synthesis and screening of substituted chalcones as lipoxygenase inhibitors

U Ahmed, SG Kaskhedikar, Z Ahmad…

文献索引:Ahmed, Umair; Kaskhedikar; Ahmad, Zafar; Ahmed, Shahzad Asian Journal of Chemistry, 2011 , vol. 23, # 11 p. 4993 - 4996

全文:HTML全文

被引用次数: 2

摘要

Abstract The present work involved the synthesis of chalcone derivatives, their characterization and in vitro evaluation for lipoxygenase inhibitory activity. The synthesis of chalcone derivatives was carried out in one step employing Claisen Schmidt condensation. Different substituted benzaldehydes viz., 3, 4, 5-trimethoxy benzaldehyde, ortho-, meta-and para-benzaldehyde, orthobromobenzaldehyde, ortho-and para-methyl benzaldehyde, ...