Abstract α-Fluoroalkenoates and 4-fluoro-5-isoxazolidinones are of vast interest due to their potential biological applications. We now demonstrate the syntheses of (E)-α- fluoroalkenoates and 4-fluoro-5-isoxazolidinones by the reactions between nitrones and α- fluoro-α-bromoacetate. By altering N-substituents in nitrones,(E)-α-fluoroalkenoates and 4- fluoro-5-isoxazolidinones can be achieved, respectively, with high chemo-and ...
