Rongalite® and base-promoted cleavage of disulfides and subsequent Michael addition to α, β-unsaturated ketones/esters: an odorless synthesis of β-sulfido …
A highly practical method to access β-sulfido carbonyl compounds was developed, which could be conducted without any expensive reagent, special apparatus/technique, and no requirement of metal catalysts. β-Sulfido carbonyl compounds were formed at room temperature, in short time and with high chemoselectivity in good to excellent yields. A plausible mechanism for the role of Rongalite®, as a promoter for the cleavage of ...
