Cyclic sulfites, key intermediates in synthesis of 1-alkylamino-3-aryloxy-2-propanols from glycidol

ZA Bredikhina, DV Savel'ev, AA Bredikhin

文献索引：Bredikhina; Savel'ev; Bredikhin Russian Journal of Organic Chemistry, 2002 , vol. 38, # 2 p. 213 - 219

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被引用次数: 19

摘要

Abstract By treating glycidol with phenols a number of 3-aryloxypropanedioles were obtained. The latter with thionyl chloride afforded 4-aryloxymethyl-1, 3, 2-dioxathiolane 2- oxides. These compounds were also obtained from 4-chloromethyl-1, 3, 2-dioxathiolane 2- oxides by substitution aryloxy group for chlorine. The cyclic sulfides synthesized are universal intermediates in the synthesis of chiral aryloxypropanolamines among which are ...