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Microwave??Assisted One??Pot Synthesis of 2??(Substituted phenyl)??1 H??benzimidazole Derivatives

G Navarrete??Vázquez, H Moreno??Diaz…

文献索引:Navarrete-Vazquez, Gabriel; Moreno-Diaz, Hermenegilda; Estrada-Soto, Samuel; Torres-Piedra, Mariana; Leon-Rivera, Ismael; Tlahuext, Hugo; Munoz-Muniz, Omar; Torres-Gomez, Hector Synthetic Communications, 2007 , vol. 37, # 17 p. 2815 - 2825

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被引用次数: 31

摘要

Abstract A series of 2??(substituted phenyl)??1 H??benzimidazole derivatives with various 5?? and 6??position substituents (??H,??CH3,??CF3) were synthesized via microwave irradiation using a short synthetic route and Na2S2O5 as oxidant. This simple, fast, and efficient preparation of benzimidazole derivatives has been developed using readily available and inexpensive reagents (aldehydes and 1, 2??phenylenediamines) under solvent??free ...