Microwave??Assisted One??Pot Synthesis of 2??(Substituted phenyl)??1 H??benzimidazole Derivatives

G Navarrete??Vázquez, H Moreno??Diaz…

Index: Navarrete-Vazquez, Gabriel; Moreno-Diaz, Hermenegilda; Estrada-Soto, Samuel; Torres-Piedra, Mariana; Leon-Rivera, Ismael; Tlahuext, Hugo; Munoz-Muniz, Omar; Torres-Gomez, Hector Synthetic Communications, 2007 , vol. 37, # 17 p. 2815 - 2825

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Citation Number: 31

Abstract

Abstract A series of 2??(substituted phenyl)??1 H??benzimidazole derivatives with various 5?? and 6??position substituents (??H,??CH3,??CF3) were synthesized via microwave irradiation using a short synthetic route and Na2S2O5 as oxidant. This simple, fast, and efficient preparation of benzimidazole derivatives has been developed using readily available and inexpensive reagents (aldehydes and 1, 2??phenylenediamines) under solvent??free ...