Chemical Communications

A catalytic deracemisation of alcohols

GRA Adair, JMJ Williams

文献索引：Adair, Gareth R. A.; Williams, Jonathan M. J. Chemical Communications, 2007 , # 25 p. 2608 - 2609

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被引用次数: 8

摘要

Our initial studies demonstrated that the use of the preformed Noyori complex RuCl 2 [(R)-BINAP][(R,R)-DPEN] 7 proved to be unsatisfactory, since unwanted aldol reactions were found to occur during the oxidation process. The use of the ruthenium hydride complex Ru(PPh 3 ) 4 H 2 in the presence of the ligands (R)-BINAP 1 and (R,R)-DPEN 3 led to clean oxidation of the alcohol into ketone , which was reduced back to alcohol with a reasonable level of ...