Several methyl 2-deoxy-2-substituted-~-arabinofuranosides (4a-e and 5b-e) to be used as intermediates in the synthesis of 2'-substituted arabinonucleosides of biomedical interest were prepared by treatment of methyl 3, 5-di-O-benzyl-2-O-(trifluoromethanesulfonyl)-a-and- 8-D-ribofuranosides 2 and 3 with the lithium, sodium, or tetrabutylammonium salts of various nucleophiles (I?-, C1-, Br-, I-, Ns-). While the a anomer 2 could be readily converted into ...
