… of 9-(2-deoxy-2-fluoro-. beta.-D-arabinofuranosyl) adenine and-hypoxanthine. An effect of C3'-endo to C2'-endo conformational shift on the reaction course of 2'- …
…, J Krzeminski, LA Ciszewski, WY Ren…
文献索引：Pankiewicz; Krzeminski; Ciszewski; Ren; Watanabe Journal of Organic Chemistry, 1992 , vol. 57, # 2 p. 553 - 559
Nucleoside 15, under the same treatment with DAST, gave the desired 2'-fluoroarabino derivative 16 exclusively in high yield. Although 18 was converted into the 2'-8-fluoro product 19 under the similar conditions, the yield was low. A plausible mechanism of formation of 12 is discussed. Deprotection of 11 and 16 afforded the desired 9-(2-deoxy-2- fluoro-~-~-arabinofuranosyl) adenine (1) and-hypoxanthine (2), respectively, in high yield. ...
