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Synthesis and evaluation of antigenic properties of peptides of the HIV-1 protein gp 41

ZD Bespalova, BL Pekelis, VI Deigin…

文献索引:Bespalova, Zhanna D.; Pekelis, Boris L.; Deigin, Vladislav I.; Yarova, Elena P.; Saks, Tatyana P.; et al. Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 10 p. 2537 - 2554

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被引用次数: 4

摘要

Abstract Scheme is described for the synthesis of 19-and 21-member peptides which constitute a part of the domain (sequence 584-609) from the conservative region of the transmembrane protein gp 41 HIV-1. The synthesis was carried out using standard methods of peptide chemistry in solution. The peptides were built from fragments which were synthesized by means of stepwise joining of amino acid residues starting from the C- ...